Magnesium plays a role in the active transport of calcium and potassium ions across cell membranes, improved attachment and growth of osteoblasts, increased proliferation of bone marrow stromal cells, with enhanced mineralization of extra- cellular matrix.

Magnesium provides stimulated proteins for enhanced bone regeneration, resulting in enhanced new bone formation through the scaffold.

Yoshizawa et al. Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, stimulation the effect of magnesium alloy degradation. Acta Biomater. 2014; 10(6): 2834-42.4 Wong et al. Engineered polycaprolactone-magnesium hybrid biodegradable porous scaffold for bone tissue engineering. Materials International. 2014; 24: 561-567.5